dacarbazine

Term ID

CHEBI:4305

Synonyms

• 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
• 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
• 4-(dimethyltriazeno)imidazole-5-carboxamide
• 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide
• 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
• 5-(3,3-dimethyltriazeno)imidazole-4-carboxamide
• 5-(dimethyltriazeno)imidazole-4-carboxamide
• dacarbazina
• dacarbazine
• dacarbazinum
• deticene
• Di-me-triazenoimidazolecarboxamide
• DIC
• DTIC
• Dtic-Dome (TN)
• HSDB 3219
• ICDMT
• Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
• NCI-C04717
• NSC 45388
• NSC-45388

Definition

A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.

References

• cas:4342-03-4
• drugbank:DB00851
• drugcentral:773
• hmdb:HMDB0014989
• kegg.compound:C06936
• kegg.drug:D00288
• lincs.smallmolecule:LSM-5487
• pubmed:10751609
• pubmed:11318431
• pubmed:12195827
• pubmed:15010317
• pubmed:20082117
• pubmed:21471822
• pubmed:21654834
• pubmed:23029050
• pubmed:23318786
• pubmed:26940170
• pubmed:28096700
• pubmed:28250333
• pubmed:28387914
• pubmed:28419676
• pubmed:29076951
• pubmed:29184162
• pubmed:29287706
• pubmed:29296081
• pubmed:29305638
• pubmed:29344241
• reaxys:521487
• wikipedia.en:Dacarbazine

Ontology

ChEBI  ( EBI )

Resources

CTD