Search Ontology:
ChEBI
3-(5-fluorouracil-1-yl)-L-alanine
- Term ID
- CHEBI:42549
- Synonyms
-
- (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid
- (S)-(-)-5-fluorowillardiine
- (S)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
- Definition
- An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).
- References
-
- CAS:140187-23-1
- DrugBank:DB02966
- KEGG:C13671
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
-
- has_role
-
Phenotype
Phenotype resulting from 3-(5-fluorouracil-1-yl)-L-alanine
Phenotype where environments contain 3-(5-fluorouracil-1-yl)-L-alanine
Phenotype modified by environments containing 3-(5-fluorouracil-1-yl)-L-alanine
Phenotype affecting 3-(5-fluorouracil-1-yl)-L-alanine
Human Disease Model