(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol

Term ID

CHEBI:42371

Synonyms

• (5R,11R)-5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
• (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
• (R,R)-cis-diethyl tetrahydro-2,8-chrysenediol
• (R,R)-cis-diethyltetrahydro-2,8-chrysenediol
• (R,R)-THC
• R,R-THC

Definition

A carbotetracyclic compound that is 5,6,11,12-tetrahydrochrysene substituted by hydroxy groups at positions 2 and 8 and by ethyl groups at positions 5 and 11 (the 5R,11R-stereoisomer). It is an agonist of ER-α and antagonist of ER-β receptors.

References

• cas:221368-54-3
• chemspider:394097
• pdb-ccd:ETC
• pubmed:11953755
• pubmed:15582497
• pubmed:18719660
• pubmed:19505948
• pubmed:20097735
• pubmed:21940647
• pubmed:22099601
• pubmed:23688559
• pubmed:23857051
• pubmed:24134630
• pubmed:25167991
• pubmed:26855429
• wikipedia.en:(R,R)-Tetrahydrochrysene

Ontology

ChEBI  ( EBI )