Search Ontology:
ChEBI

24(S),25-epoxycholesterol

Term ID
CHEBI:41633
Synonyms
  • (24S)-24,25-epoxycholest-5-en-3beta-ol
  • (24S)-24,25-epoxycholesterol
  • (24S)-25-epoxycholesterol
  • (3beta,24S)-24,25-epoxycholest-5-en-3-ol
  • 24(S),25-EC
  • 24,25-epoxy-cholesterol
  • 24S,25-epoxy-cholest-5-en-3beta-ol
  • 24S,25-epoxy-cholesterol
Definition
A 3β-hydroxy-Δ5-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor.
References
  • cas:77058-74-3
  • kegg.compound:C15632
  • lincs.smallmolecule:LSM-5712
  • lipidmaps:LMST01010012
  • pdb-ccd:CO1
  • pubmed:19426978
  • pubmed:20854813
  • pubmed:22178193
  • pubmed:22713431
  • pubmed:23130136
  • pubmed:23292650
  • pubmed:23455994
  • pubmed:24491562
  • pubmed:24747199
  • pubmed:24832732
  • reaxys:5765150
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from 24(S),25-epoxycholesterol
Phenotype where environments contain 24(S),25-epoxycholesterol
Phenotype modified by environments containing 24(S),25-epoxycholesterol
Phenotype affecting 24(S),25-epoxycholesterol
Human Disease Model