doramapimod

Term ID

CHEBI:40953

Synonyms

• 1-(3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl)-3-(4-(2-(morpholin-4-yl)ethoxy)naphthalen-1-yl)urea
• 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
• BIRB 796
• BIRB-796
• doramapimod
• N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea

Definition

A member of the class of pyrazoles that is an immunomodulator used for treatment of rheumatoid arthritis, Crohn's disease and psoriasis.

References

• cas:285983-48-4
• kegg.drug:D03736
• lincs.smallmolecule:LSM-1170
• pdb-ccd:B96
• pubmed:11896401
• pubmed:19244237
• pubmed:20655210
• pubmed:23685672
• pubmed:25358442
• pubmed:25589935
• pubmed:26044359
• pubmed:26232862
• reaxys:9170597

Ontology

ChEBI  ( EBI )