arformoterol

Term ID

CHEBI:408174

Synonyms

(-)-formoterol
(R,R)-formoterol
arformoterol
N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide

Definition

An N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide in which both of the stereocentres have R configuration. The active enantiomer of formoterol, it is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).

References

Beilstein:7861827
CAS:67346-49-0
DrugBank:DB01274
Drug_Central:4943
KEGG:D07463
PMID:15324892
PMID:18990965
PMID:20214460
PMID:20406080
Patent:US2011014246

Ontology

ChEBI ( EBI )

Relationships

is a type of: N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide

N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide Show first 5 Terms
has_role: anti-asthmatic drug beta-adrenergic agonist bronchodilator agent

anti-asthmatic drug beta-adrenergic agonist bronchodilator agent Show first 5 Terms
inverse has_part: formoterol

formoterol Show first 5 Terms
inverse is_conjugate_acid_of: arformoterol(1+)

arformoterol(1+) Show first 5 Terms
inverse is_enantiomer_of: (S,S)-formoterol

(S,S)-formoterol Show first 5 Terms
is_conjugate_base_of: arformoterol(1+)

arformoterol(1+) Show first 5 Terms
is_enantiomer_of: (S,S)-formoterol

(S,S)-formoterol Show first 5 Terms

Phenotype

Phenotype resulting from arformoterol

Phenotype where environments contain arformoterol

Phenotype modified by environments containing arformoterol

Human Disease Model