ICI-164384

Term ID

CHEBI:40710

Synonyms

• ICI 164,384
• ICI 164384
• ICI M164384
• ICI-164,384
• ICI164384
• N-butyl-11-[(7alpha,9beta,13alpha,14beta,17alpha)-3,17-dihydroxyestra-1,3,5(10)-trien-7-yl]-N-methylundecanamide
• N-butyl-11-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]-N-methyl-undecanamide
• N-butyl-11-[3,17beta-dihydroxyestra-1(10),2,4-trien-7alpha-yl]-N-methylundecanamide
• N-n-butyl-N-methyl-11-(3,17beta-dihydroxyestra-1,3,5(10)-trien-7alpha-yl)undecanamide
• N-n-butyl-N-methyl-11-[3,17beta-dihydroxyestra-1,3,5(10)-trien-7alpha-yl]undecanamide

Definition

A 3-hydroxy steroid that is 17β-estradiol substituted by a 11-[butyl(methyl)amino]-11-oxoundecyl group at position 7R. It is a steroidal antioestrogen that inhibits the cell proliferation of breast-carcinoma cell lines.

References

• cas:98007-99-9
• chemspider:94580
• drugbank:DB03860
• kegg.compound:C14758
• pdb-ccd:AOE
• pubmed:10405313
• pubmed:11174852
• pubmed:11250199
• pubmed:11597408
• pubmed:11922402
• pubmed:14713268
• pubmed:15001543
• pubmed:1570330
• pubmed:1648945
• pubmed:16781141
• pubmed:1883484
• pubmed:18848890
• pubmed:1892545
• pubmed:1915080
• pubmed:1957558
• pubmed:20306127
• pubmed:2033587
• pubmed:2325408
• pubmed:2328482
• pubmed:2391957
• pubmed:2395882
• pubmed:2582435
• pubmed:2605344
• pubmed:2761257
• pubmed:2924721
• pubmed:3199810
• pubmed:3386250
• pubmed:3559447
• pubmed:7625718
• pubmed:7625736
• pubmed:7647331
• pubmed:7779759
• pubmed:8080688
• pubmed:8117317
• pubmed:8126059
• pubmed:8219250
• pubmed:8255787
• pubmed:8314314
• pubmed:8352561
• pubmed:8669823
• pubmed:8788034
• pubmed:8836170
• pubmed:9009159
• pubmed:9879979
• wikipedia.en:ICI-164384

Ontology

ChEBI  ( EBI )

Resources

CTD