8-hydroxy-2'-deoxyguanosine

Term ID

CHEBI:40304

Synonyms

• 2'-deoxy-8-hydroxyguanosine
• 2'-deoxy-8-oxoguanosine
• 7,8-Dihydro-2'-deoxy-8-oxoguanosine
• 8-HYDROXY-2'-DEOXYGUANOSINE
• 8-Hydroxydeoxyguanosine
• 8-OHdG
• 8-Oxo-2'-deoxyguanine
• 8-oxo-2'-dG
• 8-Oxo-7,8-dihydro-2'-deoxyguanosine
• 8-Oxo-7-hydrodeoxyguanosine
• 8-Oxo-dG
• 8-Oxoguanosine

Definition

Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.

References

• cas:88847-89-6
• drugbank:DB02502
• pdb-ccd:8HG
• pubmed:11559029
• pubmed:20081197
• pubmed:9778313
• reaxys:4882818
• reaxys:5994628
• wikipedia.en:8-Oxo-2'-deoxyguanosine

Ontology

ChEBI  ( EBI )

Resources

CTD