tiratricol

Term ID

CHEBI:40021

Synonyms

2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
3,3',5-triiodothyroacetic acid
4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid
[(4-hydroxy-3-iodo-4-phenoxy)-3,5-diiodophenyl]acetic acid
[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
Emcitate
Nidolin
T3A
Teatrois
Tiracana
tiratricol
tiratricolum
TRIAC
Triax
triiodothyroacetic acid

Definition

A monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)acetic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxy-3-iodophenoxy group. It is a thyroid hormone analogue that has been used in the treatment of thyroid hormone resistance syndrome.

References

cas:51-24-1
drugbank:DB03604
drugcentral:3611
kegg.drug:D07214
lincs.smallmolecule:LSM-5706
pdb-ccd:4HY
pubmed:12059130
pubmed:12660410
pubmed:15148977
pubmed:1517383
pubmed:18715309
pubmed:18844678
pubmed:21803722
pubmed:33171841
pubmed:34174920
pubmed:36565029
pubmed:36883873
pubmed:37088711
pubmed:3783484
pubmed:37879570
pubmed:3810549
pubmed:6232590
pubmed:9215287
wikipedia.en:Tiratricol

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from tiratricol

Phenotype where environments contain tiratricol

Phenotype modified by environments containing tiratricol

Phenotype affecting tiratricol

Human Disease Model