Search Ontology:
ChEBI
carbidopa (anhydrous)
- Term ID
- CHEBI:39585
- Synonyms
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- (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
- (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
- (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid
- (S)-(-)-carbidopa
- (S)-carbidopa
- carbidopum
- L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
- L-alpha-methyldopahydrazine
- Definition
- 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
- References
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- Beilstein:4189448
- CAS:28860-95-9
- DrugBank:DB00190
- Drug_Central:496
- LINCS:LSM-5850
- PDBeChem:142
- Wikipedia:Carbidopa
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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- inverse has_functional_parent
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- inverse has_part
-
Show first 5 Terms
Phenotype
Phenotype resulting from carbidopa (anhydrous)
Phenotype where environments contain carbidopa (anhydrous)
Phenotype modified by environments containing carbidopa (anhydrous)
Human Disease / Model Data
Citations