cosyntropin

Term ID

CHEBI:3901

Synonyms

• adrenocorticotropic hormone 1-24
• alpha(1-24)-corticotrophin
• ATCH (1-24)
• beta(1-24)-corticotrophin
• corticotropin-(1-24)
• corticotropin-(1-24) tetracosapeptide
• Cosyntropin
• L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyline
• SerTyrSerMetGluHisPheArgTrpGlyLysProValGlyLysLysArgArgProValLysValTyrPro
• SYSMEHFRWGKPVGKKRRPVKVYP
• tetracosactide

Definition

A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone (corticotropin). A segment similar in all species, it contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. It is used diagnostically to investigate adrenocortical insufficiency.

References

• CAS:16960-16-0
• DrugBank:DB01284
• Drug_Central:4516
• KEGG:C06926
• KEGG:D00284

Ontology

ChEBI  ( EBI )

Resources

CTD