rosuvastatin

Term ID

CHEBI:38545

Synonyms

(3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
(3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
rosuvastatin

Definition

A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).

References

cas:287714-41-4
drugbank:DB01098
drugcentral:2406
hmdb:HMDB0015230
kegg.drug:D08492
patent:US2013035316
pubmed:17970755
pubmed:18509206
pubmed:19724024
pubmed:19956889
pubmed:23806820
pubmed:23881596
pubmed:23944632
pubmed:24072337
pubmed:24076283
pubmed:24076297
pubmed:24156555
pubmed:24163149
pubmed:24230979
pubmed:24253250
pubmed:24259612
pubmed:24304551
pubmed:24333476
pubmed:24353409
pubmed:24410968
pubmed:24417785
pubmed:24434545
pubmed:24440231
pubmed:24440960
pubmed:24444439
pubmed:24452083
pubmed:24456217
pubmed:24467235
reaxys:9670765
wikipedia.en:Rosuvastatin

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from rosuvastatin

Phenotype where environments contain rosuvastatin

Phenotype modified by environments containing rosuvastatin

Phenotype affecting rosuvastatin

Human Disease Model