clozapine

Term ID

CHEBI:3766

Synonyms

• 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
• Clozapin
• clozapina
• Clozapine
• clozapinum

Definition

A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia.

References

• beilstein:0764984
• cas:5786-21-0
• drugbank:DB00363
• drugcentral:722
• hmdb:HMDB0014507
• kegg.compound:C06924
• kegg.drug:D00283
• patent:FR1334944
• patent:NL293201
• patent:US3539573
• pubmed:18690109
• pubmed:18766167
• pubmed:20825390
• pubmed:24219174
• reaxys:764984
• wikipedia.en:Clozapine

Ontology

ChEBI  ( EBI )

Resources

CTD