cidofovir anhydrous

Term ID

CHEBI:3696

Synonyms

(S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid
(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine
(S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine
(S)-HPMPC
({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
[(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid
CDV
cidofovir
Cidofovir anhydrous

Definition

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

References

Beilstein:5080484
CAS:113852-37-2
DrugBank:DB00369
Drug_Central:639
KEGG:C06909
Patent:EP253412
Patent:US5142051
Wikipedia:Cidofovir

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: phosphonic acids pyrimidone

phosphonic acids pyrimidone Show first 5 Terms
has_role: anti-HIV agent antineoplastic agent antiviral drug photosensitizing agent

anti-HIV agent antineoplastic agent antiviral drug photosensitizing agent Show first 5 Terms
inverse has_part: cidofovir dihydrate

cidofovir dihydrate Show first 5 Terms
inverse is_conjugate_base_of: cidofovir(1-) cidofovir(2-)

cidofovir(1-) cidofovir(2-) Show first 5 Terms
is_conjugate_acid_of: cidofovir(1-) cidofovir(2-)

cidofovir(1-) cidofovir(2-) Show first 5 Terms

Phenotype

Phenotype resulting from cidofovir anhydrous

Phenotype where environments contain cidofovir anhydrous

Phenotype modified by environments containing cidofovir anhydrous

Human Disease / Model Data

Citations