chlorothiazide

Term ID

CHEBI:3640

Synonyms

• 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide
• 6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• chlorothiazide
• chlorothiazidum
• clorotiazida

Definition

4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.

References

• beilstein:1084805
• cas:58-94-6
• drugbank:DB00880
• drugcentral:609
• kegg.compound:C07461
• kegg.drug:D00519
• lincs.smallmolecule:LSM-5942
• patent:US2809194
• pubmed:10891117
• pubmed:2160536
• pubmed:28166217
• pubmed:29438107
• pubmed:3712385
• wikipedia.en:Chlorothiazide

Ontology

ChEBI  ( EBI )

Resources

CTD