Search Ontology:
ChEBI
cerivastatin
- Term ID
- CHEBI:3558
- Synonyms
-
- (3R,5S,6E)-7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-6-heptenoic acid
- (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoic acid
- (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid
- (3R,5S,E)-7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoic acid
- cerivastatin
- cerivastatin acid
- Definition
- (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
- References
-
- Beilstein:8366578
- CAS:145599-86-6
- DrugBank:DB00439
- Drug_Central:577
- KEGG:C07966
- KEGG:D07661
- PMID:17560788
- PMID:18155906
- Wikipedia:Cerivastatin
- Ontology
- ChEBI ( EBI )
- is a type of
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from cerivastatin
Phenotype where environments contain cerivastatin
Phenotype modified by environments containing cerivastatin
Human Disease / Model Data
Citations