cephalexin

Term ID

CHEBI:3534

Synonyms

• (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid
• 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid
• 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid
• Cefalexin
• cefalexina
• cefalexine
• cefalexinum
• Celexin
• Cepastar
• Cepexin
• Cephacillin
• Ceporexin
• CEX

Definition

A semisynthetic first-generation cephalosporin antibiotic having methyl and β-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.

References

• beilstein:965503
• cas:15686-71-2
• drugbank:DB00567
• drugcentral:571
• hmdb:HMDB0014707
• kegg.compound:C06895
• kegg.drug:D00263
• lincs.smallmolecule:LSM-5957
• patent:US3275626
• patent:US3507861
• pubmed:10930630
• pubmed:12569987
• pubmed:12833570
• pubmed:1384868
• pubmed:2083978
• pubmed:22559990
• pubmed:23061564
• pubmed:23457080
• pubmed:23545436
• pubmed:23688276
• pubmed:23811740
• pubmed:24268227
• pubmed:24548092
• pubmed:29017833
• reaxys:4238892
• vsdb:1791
• wikipedia.en:Cefalexin

Ontology

ChEBI  ( EBI )

Resources

CTD