cefpodoxime

Term ID

CHEBI:3504

Synonyms

• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
• cefpodoxima
• cefpodoxime
• cefpodoximum

Definition

A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.

References

• cas:80210-62-4
• drugbank:DB01416
• kegg.compound:C08114
• kegg.drug:D07650
• pubmed:20606336
• pubmed:20821175
• pubmed:21395603
• pubmed:21420838
• pubmed:21455420
• pubmed:21509928
• pubmed:21569093
• pubmed:21667000
• pubmed:29017833
• reaxys:6021381
• vsdb:2968
• wikipedia.en:Cefpodoxime

Ontology

ChEBI  ( EBI )