nocodazole

Term ID

CHEBI:34892

Synonyms

• (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester
• methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate
• methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
• methyl N-(5-thenoyl-2-benzimidazolyl)carbamate
• N-(5-(2-thenoyl)-2-benzimidazolyl)carbamic acid methyl ester
• N-(5-(2-thienoyl)-2-benzimidazolyl)carbamic acid methyl ester
• nocodazol
• nocodazole
• nocodazolum
• oncodazole
• R 17934
• R-17934
• R17,934

Definition

A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.

References

• cas:31430-18-9
• drugbank:DB08313
• kegg.compound:C13719
• kegg.drug:D05197
• lincs.smallmolecule:LSM-2260
• pdb-ccd:NZO
• pubmed:11679255
• pubmed:20399776
• pubmed:22002881
• pubmed:23869451
• pubmed:518692
• pubmed:6384770
• pubmed:7199049
• pubmed:7284368
• pubmed:7344613
• reaxys:1085978
• wikipedia.en:Nocodazole

Ontology

ChEBI  ( EBI )

Resources

CTD