nocodazole

Term ID

CHEBI:34892

Synonyms

• (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester
• methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate
• methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
• methyl N-(5-thenoyl-2-benzimidazolyl)carbamate
• N-(5-(2-thenoyl)-2-benzimidazolyl)carbamic acid methyl ester
• N-(5-(2-thienoyl)-2-benzimidazolyl)carbamic acid methyl ester
• nocodazol
• nocodazole
• nocodazolum
• oncodazole
• R 17934
• R-17934
• R17,934

Definition

A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.

References

• CAS:31430-18-9
• DrugBank:DB08313
• KEGG:C13719
• KEGG:D05197
• LINCS:LSM-2260
• PDBeChem:NZO
• PMID:11679255
• PMID:20399776
• PMID:22002881
• PMID:23869451
• PMID:518692
• PMID:6384770
• PMID:7199049
• PMID:7284368
• PMID:7344613
• Reaxys:1085978
• Wikipedia:Nocodazole

Ontology

ChEBI  ( EBI )

Resources

CTD