compactin diol lactone

Term ID

CHEBI:34652

Synonyms

(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}oxan-2-one
(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}tetrahydro-2H-pyran-2-one
Antibiotic ML 236A
compactin diol lactone
desmethylmonacolin J
ML 236A
ML-236A

Definition

A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 2-pyranones carbobicyclic compound hexahydronaphthalenes polyketide secondary alcohol

2-pyranones carbobicyclic compound hexahydronaphthalenes polyketide secondary alcohol Show first 5 Terms
has_functional_parent: ML-236C

ML-236C Show first 5 Terms
has_role: antiatherosclerotic agent anticholesteremic drug antilipemic drug antimicrobial agent EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor ... Show All 6 Terms

antiatherosclerotic agent anticholesteremic drug antilipemic drug antimicrobial agent EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor fungal metabolite Show first 5 Terms

Phenotype

Phenotype resulting from compactin diol lactone

Phenotype where environments contain compactin diol lactone

Phenotype modified by environments containing compactin diol lactone

Phenotype affecting compactin diol lactone

Human Disease Model