4-aminopyridine

Term ID

CHEBI:34385

Synonyms

4-Aminopyridine
4-AP
4-Pyridinamine
4-Pyridylamine
Ampyra
Avitrol
Dalfampridine
fampridina
fampridine
fampridinum
gamma-Aminopyridine
N07XX07
p-Aminopyridine
pyridin-4-amine

Definition

An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.

References

cas:504-24-5
drugcentral:4163
kegg.compound:C13728
kegg.drug:D04127
pdb-ccd:4AP
ppdb:1348
pubmed:11049865
pubmed:12509600
pubmed:12525889
pubmed:12853442
pubmed:12860480
pubmed:14585815
pubmed:14970964
pubmed:15052305
pubmed:15202573
pubmed:15678081
pubmed:16088375
pubmed:16417531
pubmed:16567254
pubmed:16806301
pubmed:17014896
pubmed:17071731
pubmed:17629412
pubmed:18394011
pubmed:19302905
pubmed:19443164
pubmed:19542906
pubmed:19818752
pubmed:19915712
pubmed:19966074
pubmed:20044444
pubmed:20112006
pubmed:20473651
pubmed:20967295
pubmed:21573085
pubmed:21694807
pubmed:22000073
pubmed:22073939
pubmed:22135060
pubmed:22497693
pubmed:22703551
pubmed:22936332
pubmed:23077091
pubmed:23146002
pubmed:7507992
pubmed:8208758
pubmed:8569870
pubmed:8599505
pubmed:8813586
pubmed:9178370
reaxys:105782
wikipedia.en:Dalfampridine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from 4-aminopyridine

Phenotype where environments contain 4-aminopyridine

Phenotype modified by environments containing 4-aminopyridine

Phenotype affecting 4-aminopyridine

Human Disease Model