calcein am

Term ID

CHEBI:3303

Synonyms

• [({[3',6'-bis(acetyloxy)-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthene]-2',7'-diyl]bis(methylene)nitrilo}bis[(1-oxoethane-2,1-diyl)oxy]methylene)] tetraacetate
• Calcein AM
• calcein O,O'-diacetate tetrakis(acetoxymethyl) ester
• tetrakis[(acetyloxy)methyl] 2,2',2'',2'''-{[3',6'-bis(acetyloxy)-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthene]-2',7'-diyl]bis(methanediylnitrilo)}tetraacetate

Definition

An organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases.

References

• CAS:148504-34-1
• KEGG:C11257
• PMID:30925062
• PMID:31188648
• PMID:31489142
• PMID:8107502

Ontology

ChEBI  ( EBI )

Resources

CTD