cabergoline

Term ID

CHEBI:3286

Synonyms

• (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
• (8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide
• (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
• 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
• 1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
• 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea
• cabergolina
• Cabergoline
• cabergolinum

(all 9)

Definition

An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.

References

• Beilstein:6020775
• CAS:81409-90-7
• DrugBank:DB00248
• Drug_Central:460
• HMDB:HMDB0014393
• KEGG:C08187
• KEGG:D00987
• LINCS:LSM-3939
• PMID:22075008
• PMID:22336848
• PMID:22740242
• PMID:23110560
• PMID:23743769
• Patent:BE888243
• Patent:US4526892
• VSDB:1830
• Wikipedia:Cabergoline

(all 17)

Ontology

ChEBI  ( EBI )

Resources

CTD