cabergoline

Term ID

CHEBI:3286

Synonyms

• (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
• (8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide
• (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
• 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
• 1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
• 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea
• cabergolina
• cabergoline
• cabergolinum

Definition

An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D₂ receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.

References

• beilstein:6020775
• cas:81409-90-7
• drugbank:DB00248
• drugcentral:460
• hmdb:HMDB0014393
• kegg.compound:C08187
• kegg.drug:D00987
• lincs.smallmolecule:LSM-3939
• patent:BE888243
• patent:US4526892
• pubmed:22075008
• pubmed:22336848
• pubmed:22740242
• pubmed:23110560
• pubmed:23743769
• vsdb:1830
• wikipedia.en:Cabergoline

Ontology

ChEBI  ( EBI )

Resources

CTD