4-hydroxynon-2-enal

Term ID

CHEBI:32585

Synonyms

(all 6)

Definition

An enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 4-hydroxynonenal enal hydroxyaldehyde

4-hydroxynonenal enal hydroxyaldehyde Show first 5 Terms
has subtype: (E)-4-hydroxynon-2-enal

(E)-4-hydroxynon-2-enal Show first 5 Terms
has_role: human metabolite

human metabolite Show first 5 Terms

Phenotype

Phenotype resulting from 4-hydroxynon-2-enal

Fish	Conditions	Phenotype	Term	Figures
WT	chemical treatment by environment: 4-hydroxynon-2-enal	whole organism ins expression decreased amount, abnormal whole organism pdx1 expression decreased amount, abnormal whole organism glucose increased amount, abnormal	4-hydroxynon-2-enal	Fig. 8 from Lou et al., 2020

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Phenotype where environments contain 4-hydroxynon-2-enal

Phenotype modified by environments containing 4-hydroxynon-2-enal

Fish	Modification	Conditions	Phenotype	Term	Figures
jh4Tg	ameliorated	chemical treatment by environment: carnosine, chemical treatment by environment: 4-hydroxynon-2-enal	pancreatic B cell amount, ameliorated	4-hydroxynon-2-enal carnosine	Fig. 9 from Lou et al., 2020
ml2Tg	ameliorated	chemical treatment by environment: carnosine, chemical treatment by environment: 4-hydroxynon-2-enal	pancreas size, ameliorated	4-hydroxynon-2-enal carnosine	Fig. 9 from Lou et al., 2020
y1Tg	ameliorated	chemical treatment by environment: PK-11195, chemical treatment by environment: 4-hydroxynon-2-enal	ocular blood vessel sprouting angiogenesis occurrence, ameliorated ocular blood vessel diameter, ameliorated	4-hydroxynon-2-enal PK-11195	Fig. 9 from Lou et al., 2020

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Phenotype affecting 4-hydroxynon-2-enal

Fish	Conditions	Phenotype	Term	Figures
aldh3a1^{zf3260/zf3260}	standard conditions	whole organism 4-hydroxynon-2-enal increased amount, abnormal	4-hydroxynon-2-enal	Fig. 8 from Lou et al., 2020
WT	increased food availability	brain 4-hydroxynon-2-enal increased amount, abnormal post-vent region 4-hydroxynon-2-enal increased amount, abnormal	4-hydroxynon-2-enal	2 figures from Ghaddar et al., 2021

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Human Disease Model