butorphanol

Term ID

CHEBI:3242

Synonyms

• (-)-17-(cyclobutylmethyl)morphinan-3,14-diol
• (-)-butorphanol
• (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
• 17-(cyclobutylmethyl)morphinan-3,14-diol
• butorfanol
• BUTORPHANOL
• butorphanolum

Definition

Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.

References

• beilstein:8134188
• cas:42408-82-2
• drugbank:DB00611
• drugcentral:454
• kegg.compound:C06863
• kegg.drug:D03197
• patent:DE2243961
• patent:US3775414
• patent:US3819635
• pubmed:6114178
• pubmed:6166748
• pubmed:6767032
• pubmed:6796691
• pubmed:7192744
• vsdb:1780
• wikipedia.en:Butorphanol

Ontology

ChEBI  ( EBI )

Resources

CTD