tramadol hydrochloride

Term ID

CHEBI:32250

Synonyms

(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride
(+-)-tramadol hydrochloride
rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride
racemic tramadol hydrochloride
Tramadol HCl
tramadol monohydrochloride

Definition

A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol hydrochloride. A centrally acting synthetic opioid analgesic, used to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer.

References

cas:36282-47-0
drugbank:DB00193
kegg.drug:D01355
patent:US2013011444
pubmed:21950732
pubmed:22674657
pubmed:22849674
pubmed:22871232
pubmed:22896821
pubmed:22918011
pubmed:22959557
pubmed:23029946
pubmed:23031839
pubmed:23066205
pubmed:23071920
pubmed:23103596
pubmed:23203185
pubmed:23249424
pubmed:23351340
pubmed:23363343
pubmed:23428887
pubmed:23521170
pubmed:23668411
pubmed:23724656
pubmed:23786206
pubmed:23789213
pubmed:23802666
pubmed:24019801
pubmed:24028179
reaxys:6579261
reaxys:6640634
reaxys:9237274
wikipedia.en:Tramadol

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from tramadol hydrochloride

Phenotype where environments contain tramadol hydrochloride

Phenotype modified by environments containing tramadol hydrochloride

Phenotype affecting tramadol hydrochloride

Human Disease Model