proglumide

Term ID

CHEBI:32058

Synonyms

(+-)-4-benzamido-N,N-dipropylglutaramic acid
(+-)-proglumide
(RS)-proglumide
DL-proglumide
proglumida
proglumide
proglumidum
rac-N(2)-benzoyl-N,N-dipropyl-alpha-glutamine
racemic proglumide

Definition

A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.

References

CAS:6620-60-6
Drug_Central:2281
KEGG:D01818
LINCS:LSM-4439
PMID:23247127
Patent:WO2005011665
Patent:WO2005041963
Patent:WO2005044248
Reaxys:4151696
Wikipedia:Proglumide

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (R)-proglumide (S)-proglumide

(R)-proglumide (S)-proglumide Show first 5 Terms
has_role: anti-ulcer drug cholecystokinin antagonist cholinergic antagonist delta-opioid receptor agonist drug metabolite ... Show All 8 Terms

anti-ulcer drug cholecystokinin antagonist cholinergic antagonist delta-opioid receptor agonist drug metabolite gastrointestinal drug opioid analgesic xenobiotic metabolite Show first 5 Terms
inverse has_functional_parent: proglumetacin

proglumetacin Show first 5 Terms

Phenotype

Phenotype resulting from proglumide

Phenotype where environments contain proglumide

Phenotype modified by environments containing proglumide

Human Disease Model