Search Ontology:
ChEBI

droxidopa

Term ID
CHEBI:31524
Synonyms
  • (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid
  • (2S,3R)-3,4-dihydroxy-phenylserine
  • (betaR)-beta,3-dihydroxy-L-tyrosine
  • Dops
  • droxidopa
  • droxidopum
  • Droxydopa
  • L-Dihydroxyphenylserine
  • L-DOPS
  • L-threo-dihydroxyphenylserine
  • L-Threodops
  • Northera
  • SM 5688
  • threo-Dopaserine
Definition
A serine derivative that is L-serine substituted at the β-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension
References
  • cas:23651-95-8
  • drugbank:DB06262
  • drugcentral:971
  • hmdb:HMDB0015627
  • kegg.drug:D01277
  • patent:JP2005247828
  • patent:NZ579368
  • patent:US2008221170
  • patent:US2012010293
  • patent:US2013253061
  • pubmed:11710796
  • pubmed:20063034
  • pubmed:20207766
  • pubmed:20220040
  • pubmed:21705113
  • pubmed:22561478
  • pubmed:22610782
  • pubmed:23224983
  • pubmed:24224390
  • pubmed:24326693
  • pubmed:24517276
  • pubmed:24644107
  • pubmed:24729712
  • pubmed:24883005
  • pubmed:24944260
  • pubmed:24958960
  • reaxys:7112431
  • wikipedia.en:Droxidopa
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from droxidopa
Phenotype where environments contain droxidopa
Phenotype modified by environments containing droxidopa
Phenotype affecting droxidopa
Human Disease Model