profenamine

Term ID

CHEBI:313639

Synonyms

10-(2-diethylaminopropyl)phenothiazine
10-[2-(diethylamino)-1-propyl]phenothiazine
10-[2-(diethylamino)-2-methylethyl]phenothiazine
10-[2-(diethylamino)propyl]phenothiazine
2-diethylamino-1-propyl-N-dibenzoparathiazine
ethopropazine
N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
N,N-diethyl-alpha-methyl-10H-phenothiazine-10-ethanamine
profenamina
profenamine
profenaminum

Definition

A member of the class of phenothiazines that is phenothiazine in which the hydrogen attached to the nitrogen is substituted by a 2-(diethylamino)propyl group. An antimuscarinic, it is used as the hydrochloride for the symptomatic treatment of Parkinson's disease.

References

CAS:522-00-9
DrugBank:DB00392
Drug_Central:1086
HMDB:HMDB0014536
KEGG:D08426
LINCS:LSM-1342
PMID:17459789
PMID:6539933
Patent:US2607773
Reaxys:89828
Wikipedia:Ethopropazine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: phenothiazines tertiary amino compound

phenothiazines tertiary amino compound Show first 5 Terms
has subtype: (R)-profenamine (S)-profenamine

(R)-profenamine (S)-profenamine Show first 5 Terms
has_role: adrenergic antagonist antidyskinesia agent antiparkinson drug histamine antagonist muscarinic antagonist

adrenergic antagonist antidyskinesia agent antiparkinson drug histamine antagonist muscarinic antagonist Show first 5 Terms
inverse has_part: profenamine hydrochloride

profenamine hydrochloride Show first 5 Terms

Phenotype

Phenotype resulting from profenamine

Phenotype where environments contain profenamine

Phenotype modified by environments containing profenamine

Human Disease / Model Data