camostat mesylate

Term ID

CHEBI:31347

Synonyms

• 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate methanesulfonate
• amino{4-[(4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenoxy)carbonyl]anilino}methaniminium methanesulfonate
• camostat methanesulfonate
• camostat monomethanesulfonate
• Foipan
• Foistar
• FOY 305
• FOY-305
• FOY305
• N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesulfate

Definition

A methanesulfonate (mesylate) salt prepared from equimolar amounts of camostat and methanesulfonic acid. It is a serine protease inhibitor approved and marketed in Japan in 1985 for the alleviation of acute symptoms associated with chronic pancreatitis. In 1994, it was approved for the treatment of postoperative reflux esophagitis.

References

• CAS:59721-29-8
• Chemspider:39251
• DrugBank:DBSALT002914
• KEGG:D01766
• PMID:15796165
• PMID:16677167
• PMID:17433371
• PMID:1879802
• PMID:19876587
• PMID:20574618
• PMID:21528279
• PMID:21541544
• PMID:21590090
• PMID:2455235
• PMID:25345960
• PMID:25766432
• PMID:26887332
• PMID:27408783
• PMID:30391941
• PMID:32347443
• PMID:32696234
• PMID:33176395
• PMID:33225308
• PMID:33647240
• PMID:33676899
• PMID:6590712
• PMID:7341342
• PMID:8886041

Ontology

ChEBI  ( EBI )