adefovir pivoxil

Term ID

CHEBI:31175

Synonyms

• (((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate
• ({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphoryl)bis(oxymethanediyl) bis(2,2-dimethylpropanoate)
• 9-(2-((-Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine
• 9-(2-((Bis((pivaloyloxy)methoxy)phosphinyl)methoxy)ethyl)adenine
• Adefovir dipivoxil
• GS 0840
• GS 840
• GS-0840
• hepsera
• preveon

Definition

An organic phosphonate that is the dipivoxil ester of adefovir. A prodrug for adefovir, an HIV-1 reverse transcriptase inhibitor, adefovir pivoxil is used to treat chronic hepatitis B viral infection.

References

• CAS:142340-99-6
• DrugBank:DB00718
• Drug_Central:88
• HMDB:HMDB0014856
• KEGG:D01655
• PMID:10728465
• PMID:12099163
• PMID:25237370
• PMID:25493022
• PMID:25834334
• PMID:26082614
• PMID:26110616
• PMID:26427083
• PMID:26431662
• PMID:26447622
• PMID:26462447
• PMID:26885037
• PMID:26889227
• PMID:26908332
• PMID:27010143
• PMID:27079793
• PMID:27247753
• PMID:27301512
• PMID:27386642
• PMID:27664568
• PMID:27698751
• PMID:27877054
• PMID:27977591
• PMID:28123560
• PMID:30508954
• PMID:31919749
• PMID:32159854
• PMID:32406123
• Reaxys:29413415

Ontology

ChEBI  ( EBI )

Resources

CTD