bicalutamide

Term ID

CHEBI:3090

Synonyms

• (+-)-bicalutamide
• (2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
• (RS)-4'-cyano-alpha',alpha',alpha',-trifluoro-3-(4-fluorophenylsulphonyl)-2-hydroxy-2-methylpropiono-m-toluidide
• (RS)-bicalutamide
• Bicadex
• Bical
• Bicalox
• bicalutamida
• bicalutamide
• bicalutamidum
• Bicamide
• Bicatlon
• Bicusan
• Binabic
• Bypro
• Calumid
• Calutide
• Calutol
• Casodex
• Cosudex
• ICI 176,334
• ICI 176334
• ICI-176334
• Kalumid
• Ormandyl
• rac-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
• racemic bicalutamide

Definition

A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.

References

• cas:90357-06-5
• drugbank:DB01128
• drugcentral:367
• hmdb:HMDB0015260
• kegg.compound:C08160
• kegg.drug:D00961
• lincs.smallmolecule:LSM-1437
• patent:EP100172
• patent:US4636505
• pubmed:11915584
• pubmed:12015321
• pubmed:12017896
• pubmed:12421104
• pubmed:12959312
• pubmed:15509184
• pubmed:17313204
• pubmed:18062751
• pubmed:19194583
• pubmed:23527766
• pubmed:30784326
• pubmed:31099426
• reaxys:5364666
• wikipedia.en:Bicalutamide

Ontology

ChEBI  ( EBI )