benzatropine

Term ID

CHEBI:3048

Synonyms

(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
3alpha-(diphenylmethoxy)-1alphaH,5alphaH-tropane
3alpha-(diphenylmethoxy)tropane
3alpha-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
3endo-benzhydryloxytropane
benzatropina
Benzatropine
benzatropinum
benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether
Benztropine
tropine benzohydryl ether

Definition

Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments.

References

Beilstein:90688
CAS:86-13-5
DrugBank:DB00245
Drug_Central:333
KEGG:C06846
KEGG:D07511
Patent:US2595405
Wikipedia:Benzatropine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: tertiary amino compound

tertiary amino compound Show first 5 Terms
has_role: antidyskinesia agent antiparkinson drug muscarinic antagonist oneirogen parasympatholytic

antidyskinesia agent antiparkinson drug muscarinic antagonist oneirogen parasympatholytic Show first 5 Terms
inverse has_part: benzatropine mesylate

benzatropine mesylate Show first 5 Terms

Phenotype

Phenotype resulting from benzatropine

Phenotype where environments contain benzatropine

Phenotype modified by environments containing benzatropine

Human Disease Model