benazepril

Term ID

CHEBI:3011

Synonyms

• 1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))-
• [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
• Benazepril
• benazeprilum

Definition

A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure.

References

• cas:86541-75-5
• drugbank:DB00542
• drugcentral:299
• hmdb:HMDB0014682
• kegg.compound:C06843
• kegg.drug:D07499
• lincs.smallmolecule:LSM-5609
• metacyc.compound:CPD-15329
• patent:EP72352
• patent:US4410520
• pubmed:25224804
• pubmed:25738503
• pubmed:25784709
• pubmed:25912588
• reaxys:4302258
• wikipedia.en:Benazepril

Ontology

ChEBI  ( EBI )

Resources

CTD