epothilone D

Term ID

CHEBI:29579

Synonyms

• (-)-desoxyepothilone B
• (-)-epothilone D
• (4S,7R,8S,9S,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]oxacyclohexadec-13-ene-2,6-dione
• 12,13-deoxyepothilone B
• 12,13-desoxyepothilone B
• Epo D
• epothilone D
• KOS 862
• KOS-862
• NSC 703147
• NSC-703147

Definition

An epithilone that is epithilone C in which the hydrogen at position 13 of the oxacyclohexadec-13-ene-2,6-dione macrocycle has been replaced by a methyl group.

References

• cas:189453-10-9
• drugbank:DB01873
• kegg.compound:C12039
• knapsack:C00028253
• lipidmaps:LMPK04000001
• pdb-ccd:EPD
• pubmed:10831849
• pubmed:15242255
• pubmed:15788167
• pubmed:15868148
• pubmed:17618407
• pubmed:21826439
• pubmed:22072399
• pubmed:22423084
• pubmed:23013328
• pubmed:23670541
• pubmed:23994325
• pubmed:24079664
• pubmed:24704457
• pubmed:25151331
• pubmed:25684676
• pubmed:26158758
• reaxys:7754058

Ontology

ChEBI  ( EBI )