cethromycin

Term ID

CHEBI:29506

Synonyms

• (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-ethyl-3a,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxo-11-{[3-(quinolin-3-yl)prop-2-en-1-yl]oxy}tetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside
• A-195773
• Abbott-195773
• ABT-773
• cethromycin
• cethromycine
• cethromycinum
• cetromicina
• Restanza

Definition

A macrolide antibiotic which displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. The US Food and Drug Administration (FDA) have also granted orphan drug designation to cethromycin for the treatment of anthrax prophylaxis, tularemia, and plague (PDB entry: 1NWX).

References

• cas:205110-48-1
• drugbank:DB06419
• kegg.compound:C12020
• kegg.drug:D02391
• pdb-ccd:773
• pubmed:10639382
• pubmed:12623020
• pubmed:12805263
• pubmed:15380262
• pubmed:17324007
• pubmed:18321237
• pubmed:20180612
• pubmed:21859946
• pubmed:23463743
• pubmed:31106713
• wikipedia.en:Cethromycin

Ontology

ChEBI  ( EBI )