calciol

Term ID

CHEBI:28940

Synonyms

• (+)-vitamin D3
• (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL
• (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
• (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
• (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
• activated 7-dehydrocholesterol
• calciol
• CC
• Cholecalciferol
• colecalciferol
• Delta-D
• oleovitamin D3
• vitamin D3

Definition

A hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.

References

• CAS:67-97-0
• DrugBank:DB00169
• Drug_Central:2840
• Gmelin:1267613
• HMDB:HMDB0000876
• KEGG:C05443
• KEGG:D00188
• LIPID_MAPS_instance:LMST03020000
• LIPID_MAPS_instance:LMST03020001
• PDBeChem:VD3
• PMID:10347174
• PMID:11493580
• PMID:12174089
• PMID:12955389
• PMID:15214747
• PMID:15876428
• PMID:16886665
• PMID:17156784
• PMID:184223
• PMID:19817701
• PMID:23964472
• PMID:24304198
• PMID:2838261
• PMID:2997282
• PMID:3494111
• PMID:6265326
• PMID:9627702
• PPDB:160
• Reaxys:2339331
• Wikipedia:Cholecalciferol

Ontology

ChEBI  ( EBI )

Resources

CTD