chlorambucil

Term ID

CHEBI:28830

Synonyms

• 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid
• 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
• 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
• Ambochlorin
• CHLORAMBUCIL
• chloraminophen
• gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid
• Leukeran
• N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid
• phenylbutyric acid nitrogen mustard

Definition

A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

References

• Beilstein:999011
• CAS:305-03-3
• DrugBank:DB00291
• Drug_Central:588
• KEGG:D00266
• LINCS:LSM-2645
• PDBeChem:CBL
• PMID:22025197
• PMID:22978684
• PMID:23233721
• PMID:23295789
• PMID:23521128
• PMID:23665800
• PMID:23667729
• PMID:23683018
• PMID:23725434
• PMID:23822827
• PMID:24098639
• PMID:24147900
• PMID:24223689
• Reaxys:999011
• Wikipedia:Chlorambucil

Ontology

ChEBI  ( EBI )

Resources

CTD