Search Ontology:
ChEBI
cytarabine
- Term ID
- CHEBI:28680
- Synonyms
-
- 1-beta-D-Arabinofuranosylcytosine
- 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
- 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
- ara-C
- arabinocytosine
- Arabinoside C
- citarabina
- Cytarabine
- cytarabinum
- Cytosine arabinoside
- Cytosine-1-beta-D-arabinofuranoside
- cytosine-beta-D-arabinofuranoside
- Definition
- A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a β-N1-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
- References
-
- cas:147-94-4
- drugbank:DB00987
- drugcentral:770
- hmdb:HMDB0015122
- kegg.compound:C02961
- kegg.drug:D00168
- lincs.smallmolecule:LSM-5470
- pdb-ccd:AR3
- pubmed:15492802
- reaxys:89175
- wikipedia.en:Cytarabine
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from cytarabine
Phenotype where environments contain cytarabine
Phenotype modified by environments containing cytarabine
Phenotype affecting cytarabine
Human Disease Model