cycloheximide

Term ID

CHEBI:27641

Synonyms

• 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide
• 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
• cicloheximida
• cicloheximide
• cicloheximidum
• Cycloheximid
• cycloheximide
• naramycin
• naramycin A
• Zykloheximid

Definition

A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.

References

• cas:66-81-9
• kegg.compound:C06685
• kegg.drug:D03625
• knapsack:C00047211
• lincs.smallmolecule:LSM-2791
• pdb-ccd:3HE
• ppdb:1680
• pubmed:11972861
• pubmed:16659174
• pubmed:25209664
• pubmed:26715760
• pubmed:27192630
• pubmed:27665925
• pubmed:30154175
• pubmed:30916348
• pubmed:32299921
• pubmed:33101237
• reaxys:88868
• wikipedia.en:Cycloheximide

Ontology

ChEBI  ( EBI )

Resources

CTD