amrinone

Term ID

CHEBI:2686

Synonyms

• 3-amino-5-(4-pyridinyl)-1,2-dihydro-2-pyridone
• 3-amino-5-(4-pyridinyl)-2(1H)-pyridinone
• 3-amino-5-(pyridin-4-yl)pyridin-2(1H)-one
• 3-amino-5-pyridin-4-yl-1H-pyridin-2-one
• 5-amino-1,6-dihydro-6-oxo-[3,4'-bipyridine]
• 5-amino[3,4'-bipyridin]-6(1H)-one
• amrinona
• amrinone
• amrinonum
• inamrinone
• WIN 40680
• WIN-40680

Definition

A 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.

References

• cas:60719-84-8
• drugbank:DB01427
• drugcentral:201
• hmdb:HMDB0015496
• kegg.drug:D00231
• lincs.smallmolecule:LSM-6600
• pubmed:10513074
• pubmed:10835763
• pubmed:10919416
• pubmed:10969688
• pubmed:10972600
• pubmed:12076859
• pubmed:12111179
• pubmed:12354747
• pubmed:14754535
• pubmed:15064331
• pubmed:15892406
• pubmed:15972057
• pubmed:16154150
• pubmed:16236146
• pubmed:17582263
• pubmed:18468627
• pubmed:23112975
• pubmed:23184630
• pubmed:23908328
• pubmed:28166217
• pubmed:29764757
• pubmed:31194440
• pubmed:3764113
• pubmed:3916118
• pubmed:39684
• pubmed:7379253
• wikipedia.en:Amrinone

Ontology

ChEBI  ( EBI )

Resources

CTD