amiloride

Term ID

CHEBI:2639

Synonyms

3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide
3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
amilorida
amiloride
amiloridum
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide

Definition

A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid.

References

Beilstein:616612
CAS:2609-46-3
DrugBank:DB00594
Drug_Central:158
HMDB:HMDB0014732
KEGG:C06821
KEGG:D07447
LINCS:LSM-4194
MetaCyc:CPD-10324
PDBeChem:AMR
PMID:16020936
PMID:24410943
PMID:24419567
PMID:9124403
Patent:BE639386
Patent:US3313813
Reaxys:657410
Wikipedia:Amiloride

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: aromatic amine guanidines organochlorine compound pyrazines

aromatic amine guanidines organochlorine compound pyrazines Show first 5 Terms
has_role: diuretic sodium channel blocker

diuretic sodium channel blocker Show first 5 Terms
inverse has_functional_parent: 5-(N,N-hexamethylene)amiloride 5-(N-methyl-N-propyl)amiloride ethylisopropylamiloride

5-(N,N-hexamethylene)amiloride 5-(N-methyl-N-propyl)amiloride ethylisopropylamiloride Show first 5 Terms
inverse is_conjugate_acid_of: amiloride(1+)

amiloride(1+) Show first 5 Terms
is_conjugate_base_of: amiloride(1+)

amiloride(1+) Show first 5 Terms

Phenotype

Phenotype resulting from amiloride

Phenotype where environments contain amiloride

Phenotype modified by environments containing amiloride

Human Disease Model