Search Ontology:
ChEBI
adefovir
- Term ID
- CHEBI:2469
- Synonyms
-
- 9-(2-(Phosphonomethoxy)ethyl)adenine
- 9-(2-Phosphonylmethoxyethyl)adenine
- Adefovir
- DRG-0156
- GS 0393
- GS 393
- GS-0393
- HSDB 8079
- N-(2-Phosphonylmethoxyethyl)adenine
- PMEA
- {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid
- Definition
- A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection.
- References
-
- CAS:106941-25-7
- DrugBank:DB00718
- KEGG:C11277
- KEGG:D02768
- PDBeChem:5HG
- PMID:10676990
- PMID:11796353
- PMID:14647052
- PMID:14978283
- PMID:15866657
- PMID:22976988
- PMID:24338503
- PMID:27079793
- PMID:27381944
- PMID:27649318
- PMID:27664568
- PMID:27698751
- PMID:27729626
- PMID:27746441
- PMID:27806120
- PMID:27858892
- PMID:27880997
- PMID:27977591
- PMID:28011962
- PMID:28079295
- PMID:28081595
- PMID:28123560
- PMID:28322924
- PMID:28397817
- PMID:28436380
- Reaxys:3561094
- Wikipedia:Adefovir
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_functional_parent
-
- has_role
-
- inverse has_functional_parent
-
- inverse is_conjugate_base_of
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- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from adefovir
Phenotype where environments contain adefovir
Phenotype modified by environments containing adefovir
Phenotype affecting adefovir
Human Disease Model