Search Ontology:
ChEBI

thiamet G

Term ID
CHEBI:233586
Synonyms
  • (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
  • 2-(ethylamino)-3aR,6S,7R,7aR-tetrahydro-5R-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol
  • thiamet-G
Definition
A pyranothiazole that is (3aR,7aR)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole substituted by an ethylamino, hydroxymethyl, hydroxy, and hydroxy groups at positions 2, 5R, 6S, and 7R. It is a potent and selective inhibitor of O-GlcNAcase (Ki = 21 nM).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from thiamet G
Phenotype where environments contain thiamet G
Phenotype modified by environments containing thiamet G
Phenotype affecting thiamet G
Human Disease Model