BAM15

Term ID

CHEBI:233585

Synonyms

5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
BAM 15
BAM-15
N(5),N(6)-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
N,N'-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Definition

An organic heterobicyclic compound that is [1,2,5]oxadiazolo[3,4-b]pyrazine substituted by (2-fluorophenyl)amino groups at positions 5 and 6. It is a mitochondrial protonophore uncoupler that is a potential treatment for obesity and sepsis.

References

cas:210302-17-3
pmc:PMC8090152
pubmed:30505660
pubmed:30795805
pubmed:32409697
pubmed:32519812
pubmed:32971482
pubmed:34062536
pubmed:34627389
pubmed:35192847
pubmed:35628259
pubmed:36422268
pubmed:36757801
pubmed:36914795
pubmed:37793464
pubmed:37870907
pubmed:37900126
pubmed:38140036
pubmed:38315575
pubmed:38343281
pubmed:38424591
pubmed:39152636
pubmed:39168228
pubmed:39406121
pubmed:39533750
pubmed:39549173
pubmed:39614818
pubmed:39650017
pubmed:39740573
wikipedia.en:BAM15

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from BAM15

Phenotype where environments contain BAM15

Phenotype modified by environments containing BAM15

Phenotype affecting BAM15

Human Disease Model