ISOX DUAL

Term ID

CHEBI:233360

Synonyms

• 1962928-22-8
• [3-[4-[2-[5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl]ethyl]phenoxy]propyl]dimethylamine

Definition

ISOX DUAL is a dual CBP/p300 and BRD4 bromodomain inhibitor (IC50 values are 0.65 and 1.5 uM for CBP and BRD4 respectively). Downregulates IL-6, IL-1b and IFN-b in macrophages.

References

• CAS:1962928-22-8

Ontology

ChEBI  ( EBI )