Search Ontology:
ChEBI

BI-4020

Term ID
CHEBI:232716
Synonyms
  • [10(10a)E,18R]-1,6,18-trimethyl-14-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-1H,17H-8,4-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-9(11H)-one
  • BI 4020
  • BI4020
Definition
A macrocycle with formula C30H38N8O2. It is a potent inhibitor of triple mutant EGFR(del19 T790M C797S) variant and shows efficacy for regressing tumor xenografts in vivo.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from BI-4020
Phenotype where environments contain BI-4020
Phenotype modified by environments containing BI-4020
Human Disease Model
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.