Search Ontology:
ChEBI

LCS3

Term ID
CHEBI:232545
Synonyms
  • N-(4-chlorophenyl)-5-nitro-2-furancarboxamide
  • N-(4-chlorophenyl)-5-nitrofuran-2-carboxamide
  • NSC761634
Definition
LCS3 is a reversible and uncompetitive glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) inhibitor (IC50=3.3 uM and 3.8 uM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis. LCS3 can be used in lung adenocarcinoma (LUAD) research.
References
  • CAS:109844-92-0
Ontology
ChEBI  ( EBI )
Relationships
is a type of
Phenotype
Phenotype resulting from LCS3
Phenotype where environments contain LCS3
Phenotype modified by environments containing LCS3
Human Disease Model
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