Search Ontology:
ChEBI
SLC-0111
- Term ID
- CHEBI:232342
- Synonyms
-
- 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea
- 4-(4-fluorophenylureido)-benzenesulfonamide
- 4-[3-(4-fluorophenyl)ureido]benzenesulfonamide
- 4-{[(4-fluorophenyl)carbamoyl]amino}benzene-1-sulfonamide
- 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide
- MST-104
- NSC-213841
- SLC 0111
- SLC0111
- U 104
- U-104
- U104
- WBI-5111
- Definition
- It is a potent carbonic anhydrase inhibitor (Ki = 45.1 nM and 4.5 nM for CA IX and CA XII, respectively) that is in clinical trials for the treatment of hypoxic malignancies .
- References
-
- CAS:178606-66-1
- DrugBank:DB18815
- PDBeChem:WWZ
- PMCID:PMC5693064
- PMID:20922253
- PMID:26810836
- PMID:28347633
- PMID:28363153
- PMID:28947945
- PMID:29263302
- PMID:29962205
- PMID:30362384
- PMID:30445264
- PMID:30471577
- PMID:30978604
- PMID:32251122
- PMID:32396749
- PMID:32738591
- PMID:33667848
- PMID:33773285
- PMID:34221901
- PMID:34232641
- PMID:34871842
- PMID:34894950
- PMID:35328549
- PMID:35365193
- PMID:36146927
- PMID:36776327
- PMID:36982873
- PMID:37321108
- PMID:37501287
- PMID:37549770
- PMID:38713910
- PMID:39316272
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from SLC-0111
Phenotype where environments contain SLC-0111
Phenotype modified by environments containing SLC-0111
Human Disease Model