Search Ontology:
ChEBI
dordaviprone
- Term ID
- CHEBI:232328
- Synonyms
-
- 11-benzyl-7-[(2-methylphenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.0(2,6)]trideca-1(9),5-dien-8-one
- 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one
- dordaviprona
- dordaviprone
- dordavipronum
- ONC 201
- ONC-201
- ONC201
- TIC 10
- TIC-10
- TIC10
- Definition
- An organic heterotricyclic compound that is 2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one substituted by 2-methylbenzyl and benzyl groups at positions 4 and 7, respectively. It is a selective antagonist of the dopamine receptor D2 and an allosteric agonist of mitochondrial protease caseinolytic protease P.
- References
-
- CAS:1616632-77-9
- DrugBank:DB14844
- KEGG:D12733
- PMCID:PMC10402351
- PMCID:PMC10489515
- PMCID:PMC11182913
- PMCID:PMC11183467
- PMCID:PMC11183998
- PMCID:PMC7650907
- PMCID:PMC8598719
- PMCID:PMC9354166
- PMID:34900991
- PMID:35261798
- PMID:35491654
- PMID:35693092
- PMID:36555190
- PMID:36672458
- PMID:37279797
- PMID:37589388
- PMID:37772709
- PMID:37846673
- PMID:38011799
- PMID:38187068
- PMID:38335473
- PMID:38386699
- PMID:38400780
- PMID:38445964
- PMID:38554031
- PMID:38588460
- PMID:38859853
- PMID:39110925
- PMID:39172943
- PMID:39425129
- Wikipedia:Dordaviprone
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from dordaviprone
Phenotype where environments contain dordaviprone
Phenotype modified by environments containing dordaviprone
Human Disease Model