Search Ontology:
ChEBI

dordaviprone

Term ID
CHEBI:232328
Synonyms
  • 11-benzyl-7-[(2-methylphenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.0(2,6)]trideca-1(9),5-dien-8-one
  • 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one
  • dordaviprona
  • dordaviprone
  • dordavipronum
  • ONC 201
  • ONC-201
  • ONC201
  • TIC 10
  • TIC-10
  • TIC10
Definition
An organic heterotricyclic compound that is 2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one substituted by 2-methylbenzyl and benzyl groups at positions 4 and 7, respectively. It is a selective antagonist of the dopamine receptor D2 and an allosteric agonist of mitochondrial protease caseinolytic protease P.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from dordaviprone
Phenotype where environments contain dordaviprone
Phenotype modified by environments containing dordaviprone
Human Disease Model